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On Wednesday, the Centers for Disease Control and Prevention (CDC) released an uplifting report regarding the significant reductions in U.S. drug overdose fatalities, which decreased in 2024 to their lowest figures in five years.
The reduction from 110,037 fatalities in 2023 to 80,391 in 2024 — a drop of 26.9% — indicates a favorable trend. This decrease signifies the lowest rate since 2019, with fatalities rising sharply during the pandemic from 2020 to 2022.
A reduction in fatalities was observed across multiple drug categories, especially synthetic opioids like fentanyl, which declined from 76,282 in 2023 to 48,422 in 2024.
Dr. Mohamed Kabbaj, a professor at Florida State University College of Medicine, engages in extensive research in the realms of stress, substance dependence, and social behaviors. The Kabbaj Lab explores individual variations in stress responses and reactions to addictive substances.
Kabbaj perceives the CDC report on the reduction in U.S. drug overdose fatalities as a positive development but remains cautiously hopeful due to concerning trends in certain states.
“This is heartening news, as any reduction in drug overdoses and lives preserved is a step in the right direction,” Kabbaj stated. “The almost 50% drop in opioid overdoses is particularly encouraging. However, as the report indicates, we are merely returning to levels seen before the opioid crisis. Although most states are witnessing reductions, some — such as South Dakota and Nevada — are still facing increasing overdose rates, particularly involving fentanyl.
“This could be associated with elevated levels of alcohol consumption in these states, as the combination of alcohol and fentanyl poses significant risks and may be contributing to the rising overdose figures.”
Media inquiries for Kabbaj can reach him via email at [email protected].
Dr. Mohamed Kabbaj, professor and director of the Kabbaj Lab, College of Medicine
As a specialist in substance dependence, what do you believe are the primary factors in the steep decline of U.S. drug overdose fatalities?
“Numerous elements likely contribute to this favorable trend. The increased accessibility of Narcan, the opioid overdose reversal medication — especially among first responders — has likely saved countless lives. Its recent FDA approval as an over-the-counter drug has further enhanced public access. Furthermore, awareness initiatives by the media and education systems have been crucial in informing individuals about the risks of drug use and the lifesaving potential of Narcan. The DEA has also made notable progress in regulating prescription opioids, leading physicians to be significantly more prudent in prescribing these drugs. Additionally, improved border enforcement may have played a role in decreasing the influx of illegal drugs, particularly fentanyl, into the United States.”
Is there anything further that needs to be done to guarantee that overdose rates continue to decrease?
“As opioid overdose remains a critical public health concern, it’s vital to continue championing broader and more affordable availability of Narcan. Education regarding the hazards of drug use should commence as early as possible — ideally before adolescence, a crucial development period when many start experimenting with substances. As with numerous health challenges, prevention is essential. Efforts to diminish the availability of harmful drugs — such as heightened border enforcement aimed at fentanyl and cocaine, alongside domestic drug regulation — are also crucial. Moreover, healthcare providers must remain vigilant in prescribing opioids, ensuring they are utilized only when genuinely necessary and in appropriate amounts.”
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